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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8b0610d925114ed3df31f2eab184387627d4cdf83ec89cb25ab3127cda1b4d66' 
  AND token = 'WPqsQ4tUd0m/DbG2+Oj6XUwxB2AjU3s7k8QfqpOkb0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}