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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad6adb9858a12321996d28173fd360170eb862f52a3249e1a9450c66cc70db2e' 
  AND token = 'Q4UKr1fUC1TbshsaN+YJadJJ40C2K27MbgTlPRtYxoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}