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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c3d6f7b4355f960cc923effef5493366f8f36f06f0a9f207d2ac863e67d4b360' 
  AND token = '0XnWBD3aTizwFQ2IUVRxISbi7E00Qc6oBgjTQHhbc6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}