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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7d42958a6523dc1c657712587b271cd31a8c0b970fae864ecb765c79200fa566' 
  AND token = 'HEkeNHKhXRkzAs73298skFIpblq91XcIxC/RroPkEF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}