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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10f4163e085896950cb69d9f65aacfaf4ef58cac88f61f1209471dde1f5efebe' 
  AND token = 'MQ5VhMoHX+L5+yVriVBCjySJ/KYgpDHSrXAdjVe+Q5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}