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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2496bf9aabf7e29ceb91d28da3d951c305105ab78c1af94935621c3f5f0df3f3' 
  AND token = 'iSap5aqgqxv+yTfpF7JVn48NY2WSOq7YuxuoVOvamPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}