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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5c597ec131dfc718dd17d6ff05b175dcffdff1b265b2f546f4d563aececf78b8' 
  AND token = '4h+FML0y24NM1D4ZsCy9ikN7JMeukocBCR46lUthq78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}