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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd3d21097806baa782a047d74580d9422135b2f8bdfd860eb24386e644f42f650' 
  AND token = 'H9wnmx15CA+QyhQ+obL8ahVb5VS0ZoqON+A3wn4Sps0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}