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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '48924a1b9326fa82a98d7dfb20113626df80d2ad6d3744efb61a0906c90f3f70' 
  AND token = 'HcBTxGuDUHAQj4lZ6Gc1167OKo8pNdAtwDSRGxV/gcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}