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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9a157ffa5d32c19169d1930d66d916763dacaa70be38b1fe67928fabb4dbe6c0' 
  AND token = 'XUeb0Fh+rjBoLcRkIiD4Fh3F7W8+oc7oh1V6E871rfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}