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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea5500964344335787bfbbf27ab28d88533fb806725ab0a1a16bf442267c0e07' 
  AND token = '+dDTE1y+R/TidTmSw2r75XV20glky3j5FHh63nTTN98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}