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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '144e186b3de026c5b6878ca4396a3dea5015f72f5847aa1096ebbf447a3708f3' 
  AND token = 'CnuphIfTEjt+26aQKkAz6HvFIMAaLW3UQg4xKHtLrS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}