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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01fdd29c1f465ad5598bc1cdd630e4144bae51481dc2b692b655110f4ee7bc52' 
  AND token = 'tN25tJFpqNQ12NO6BSKBiEp+iTzNCS2tHcDywgB7ekg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}