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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '709fecba475d152ad6777c29a3ca0c3c22ca347357f7706ce7a4ccc5e4b78022' 
  AND token = 'UrpenAYRsQI5+3fjjjctlA3YQa6KSE1xPP6UpAIxTm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}