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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3457acd1363c4f1b381e08cabe755d0ea0e929a5bc07e61c31709423687f7c0e' 
  AND token = '67t71XRwBLD0fXwginuZfaK3/S5mGcFjWCtii8WTP2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}