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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cc39a09024298d799d6b4112288f938e00fbbe1468d768fe214d9cf501938e00' 
  AND token = 'qGpdNKU8nXaQEo9EgUD/ITxaFZp6tjI2+dRTEKW/q70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}