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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80ab7749d8a3efbe8321085e8387b2f5070fd25270ecd566aa3af65a09962d5e' 
  AND token = 'vXKnsXp+rzv6RZuXoASU2k0lwBluapQp9Sd8xoSdpDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}