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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '77ac07a344ebcd1b78f2c662f464b67f216842de379eed81cc6be89c252080b7' 
  AND token = '00ZJC3hVZdYk/Up4oxfr1x2dsdD+81IRmEo8mR4DPdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}