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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c82e5546000f6db4368d15d9c55126fde0cc94ab0b6ba2030fa1436140d20f3d' 
  AND token = 'e/dYGn1zt4ZikAwM5+zDTyx/0mthbT2K3aDZL3xZ45E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}