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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0cb1004f58ea7311e2915b1a66f6c65d64487200549af252bff34a621a5b3335' 
  AND token = 'Mmww+cwRf+yI5UARJ/hXJCLEAtEChx1wzc5t40weaJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}