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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '111af5f395b177f4589ca3903989504086f3577837df3df2071863725c172f19' 
  AND token = '2WJfCIMsbwt/YMbOWFrKLk0YBw6/MraMB29C/xa1jWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}