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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '686cf3de9fa8adddbf4603b5510794d1f8324cc0e201082b9fee838335431d78' 
  AND token = 'nCoSSDH/0MuV5lW6ekO94tgNmmU4BkV3ymaqwbaa/74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}