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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d7ff51d9b308cdb321f163246c4bc2d45ee05d08b320b1aa594945755a2deb8' 
  AND token = 'ZYzBbOWj3vLp9NpzoeC3EYF95pgpvLqHk1nlgLpPrro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}