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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1ace56dde316efb4f324ddf3078fdb17b907116a0f9380c54a5cfc211b456111' 
  AND token = 'C9KlAspFNN5A9HTzhv03+KJh0LIWf6impfycTC+nOC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}