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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '654e07e2a9adea0e8c2ee36cece2fdb510bf044bfc19bdd2e4d45455f34d825d' 
  AND token = 'yf6tS0pGp9R0aox6z4lkAZUU3GvzGNTHNGGkGY21OP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}