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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '70510f2e27a1f0e2a5ef8eb1bb2406b236ebe2f174d70b00e853b47f7a3a886c' 
  AND token = 'MpeBlOMks1335ABwZTKWj3LpB3YCc4hRqzU1cdYF4oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}