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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dd998242760ddfe634a76cde6faca952d65ac627163ecfbd861c6ef7fbbb12d5' 
  AND token = 'EI2GmDyNcv3ACPMYWZ4+UtUqbDOSf4JkzPkHNlScSM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}