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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e2a0542b9881a16bcea4751217a61f05fa792509aa06f1e5d6980776413e8f4' 
  AND token = '160RB2dj329rSL3GnYA7PuUc8ZYhRQLdNNRH8UKXeM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}