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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '380adc186daa1b436c371e01a49e6871613c53416464cf3803e7d9ff58e96556' 
  AND token = 'd8Ocq+vO14TBBQEuKCQi4DYjpXyqL7l2AQDPMdyscqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}