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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7221110d4b6ab4e639905051c44b8e9a2089b915221abefc15fb466b38eac86a' 
  AND token = 'lpA5K10PrQEzVbN0RYHAIF6N2IROkwYvnm+yjGKXAuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}