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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21ae05eea4f3890bef85fbae25a7e95247e65f42e2127892f686838b5e5680ef' 
  AND token = 't13iymX5B49/npG9GUYSPGjvGYhwpmqW4L+5wNxM9SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}