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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2281b6a2167f3b3171c5c5500299b8f7bd1ff7ee8f07692bed2ab2c6504c7e06' 
  AND token = 'r5KJgtctc6vDt1xYit9O6pDN4GtjGbMBRCAvAzYuAj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}