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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '653f6832d8ff0d7f2ed913eb14f278ed34d63c4177e003bb3f5352bd5b5c4336' 
  AND token = '2FxeZckL0gwA7fOfMa0s8PuRCxGQJpjh0DcA/gx9tyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}