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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21d6d79a8b944acf61ac2fdf625a8ddedfe205630ef3b55914b4ac894fc0b490' 
  AND token = 'vHnzyBotwpPfAb2Y51VyEZP0hVnWz/FmaeAd/ZBE3a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}