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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3939be691110d81408b305bce391af7c6627fe087295c52738085000b7fb19f8' 
  AND token = 'DWaRnMGE54OizK+26bD2mINlTxVACDWnhw9RTnldcy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}