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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2077d19cb123ab5dd481bd43aac46152daaaf64d1fb49f92e5484cc627dad500' 
  AND token = 'z+zc8SGsPX+CyoIBOcV4yNN6nbBFxmpNr2BXpxHRMMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}