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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49010e99b742fed17c1cb2c80b496ad205b2333f00910b04b3c7f48b6e6852a3' 
  AND token = 'u3geKTuGsdIo1lAU1RK0ipcM16lGuA0Rcgh6jfoaC40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}