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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b2f18ec4cfc729b2fe22e1d86614334f05467f273e807cf4d07843d2dd22c877' 
  AND token = 'YeoU0mmD+zE+zCMpE/5/cTeWP63VATZWexhTn8kCZEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}