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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e230d709efb35871450ef2cf77570ebfc7d0b93672fdabf78a099db4a40fe534' 
  AND token = '1toRriXlCl1XOSM+V4a6FMGmZUH6GwnwcErTPeklFCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}