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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8b8ea44286ed2da2789c6384dfba24be296c0772fbf9f038c8ff9081ee64cd0a' 
  AND token = 'zfLjyzxyFma4g+6UDCm0v/NSL1rBh2Y0BB6d4iO9W2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}