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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '465ad91105d10ae448ef13b181e1cb648eedef223641a88a1ddc3300fc1f833f' 
  AND token = 'MFLj/84m1MUiNKUvJYkcxxLt3bt6O8uPkIuWHv3Wpw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}