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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5db209005c270bb14a6a7d830501201fee46bb69dbc457e6f62342258f8620b' 
  AND token = 'feaaoJs7X1OMThtMJH3kc6fBydkQQ1kZ9zFxHfvTYKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}