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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a66914c4f3e48a926aebe73a259e9d5c6663a12825d559db96770a3cf497fc28' 
  AND token = 'MegXDm9RK1Re8f437QqniWjM+0txWD3Hrwl0GmdpTzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}