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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '624b6207b802c2d27b6cab252f48802dea67f452ba009f30671282d0368faa6d' 
  AND token = '8627d3317XHbMYvFln5S5eSHLmSZCMPyKqfbiaUPbcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}