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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42fb0d9659ac9554ad7756747ffd8735b2df0714fa805a7bb2e81abccb86ce66' 
  AND token = 'vwaXNKkZxLGBV0zfO9m77MnulMcvc4fmPEktourySDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}