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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42a36a7f1681d2c5e07d254d948f7cef32ee7b8861ee9e25ee578c419bf85a95' 
  AND token = 'UnhVYpY0nK+oaZQv8H6cbYmg3bRtvMZoY2r8LogNRPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}