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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad8352b093bf105c11c05066c8f5edfb94e8faee97d55b9fdc30cefe1cd48186' 
  AND token = 'Ju1Sd4uKo/HisOyF2KqUOgoNkmyPNBIwEQuTKGUeoOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}