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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22fcf06f1916ae1f7649e2fe3fd12d26482a835744854b57fb1ab53e693e3754' 
  AND token = 'pAy+R5VM4T30ARNpyeX2GPIrsH27Hwuv+EJ8C4K0IrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}