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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '384c41de762a7a7de61d2bebc92d9f21502baf25f0252401d43d05aa7bddf8b3' 
  AND token = 'NPMwAOXXggc1Ua1hd5dvtZcUhpb4YQAyNbcPehDs3m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}