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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '51e44829daafdf4baec35efdacf67b76aba4da219bd2dd6cdcc2a35460d7a745' 
  AND token = 'IdRF1ECPB/OJXLGfYkH9mmVF593zKgG7zBnmL2nfE2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}